Risk Factors of Delayed Graft Function in Patients with Kidney Transplantation

Authors

  • Oyunpurev Erdenechimeg The First Central Hospital of Mongolia, Ulaanbaatar, Mongolia
  • Tuvshinbayar Javzan The First Central Hospital of Mongolia, Ulaanbaatar, Mongolia
  • Uugan-Erdene Amarbold The First Central Hospital of Mongolia, Ulaanbaatar, Mongolia
  • Od-Erdene Lkhaakhuu The First Central Hospital of Mongolia, Ulaanbaatar, Mongolia
  • Kishgee Tseren The First Central Hospital of Mongolia, Ulaanbaatar, Mongolia
  • Nyamsuren Davaajav The First Central Hospital of Mongolia, Ulaanbaatar, Mongolia
  • Bayan-Undur Dagvadorj The First Central Hospital of Mongolia, Ulaanbaatar, Mongolia
  • Erdenesaikhan Mendbayar The First Central Hospital of Mongolia, Ulaanbaatar, Mongolia
  • Ganbold Gantulga The First Central Hospital of Mongolia, Ulaanbaatar, Mongolia
  • Javkhlantugs Dondog The First Central Hospital of Mongolia, Ulaanbaatar, Mongolia
  • Zolzaya Nyamsuren The First Central Hospital of Mongolia, Ulaanbaatar, Mongolia
  • Sarantsetseg Jigjidsuren The First Central Hospital of Mongolia, Ulaanbaatar, Mongolia
  • Oyunbileg Banzragch The First Central Hospital of Mongolia, Ulaanbaatar, Mongolia
  • Batsaikhan Batsuuri The First Central Hospital of Mongolia, Ulaanbaatar, Mongolia
  • Tumurbaatar Batchuluun The First Central Hospital of Mongolia, Ulaanbaatar, Mongolia
  • Tsogjargal Burentogtokh The First Central Hospital of Mongolia, Ulaanbaatar, Mongolia
  • Enkhtuya Jambaldorj Mongolian National University of Medical Sciences, Ulaanbaatar, Mongolia
  • Enkhtamir Enkhtuvshin Mongolian National University of Medical Sciences, Ulaanbaatar, Mongolia
  • Ariunbold Jamba The First Central Hospital of Mongolia, Ulaanbaatar, Mongolia

DOI:

https://doi.org/10.24079/cajms.2025.03.005

Keywords:

kidney transplantation, delayed graft function, DGF, graft function, kidney graft, Mongolia

Abstract

Objective: In Mongolia, since 2006, kidney transplantation has been performed regularly, with more than 400 people having undergone this surgery. This preliminary study aimed to investigate the incidence of delayed graft function after kidney transplantation in Mongolia and to identify the associated risk factors. Methods: This study used a retrospective approach, gathering data from monitoring records. We applied the Student t-test, one-way ANOVA, Wilcoxon rank sum test, Kruskal-Wallis rank test, Spearman correlation, multivariate linear regression, and logistic regression. Results: Of the 268 recipients, 198(74.44%) were male. There were 14 total cases of DGF, of which 13 were transplanted from brain-dead donors. Postoperative urine outcome decreases by 120 mL for a 1-year increase in donor age (b = -120, p= 0.033). A 1-minute increase in cold ischemia time results in a 20-mL decrease in urine output (b = -20, p= 0.002). Donor age>40 increased the risk by 1.2 times (OR=1.2, p= 0.05), and brain-dead donor increased the risk by 19.37 times (OR=19.37, p= 0.0001), while recipient age<35 reduced the risk by 5 times (OR=0.2, p= 0.039). Conclusion: Our study found that risk factors such as older donor and recipient age, prolonged cold and warm ischemia times, and brain-dead donor status were associated with an increased risk of delayed graft function.

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References

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Published

2025-09-30

How to Cite

Erdenechimeg, O., Javzan, T., Amarbold, U.-E., Lkhaakhuu, O.-E., Tseren, K., Davaajav, N., … Jamba, A. (2025). Risk Factors of Delayed Graft Function in Patients with Kidney Transplantation. Central Asian Journal of Medical Sciences, 11(3), 145–154. https://doi.org/10.24079/cajms.2025.03.005

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